For more than twenty-five years, the Agencia para el Desarrollo de la Mosquitia (MOPAWI, Agency for the Development of the Mosquitia) has worked to engage local and indigenous communities in the integrated management of the Río Plátano Biosphere Reserve and other protected areas in northeastern Honduras. Located within the Mosquitia area, the reserve contains the largest intact rainforest north of the Amazon, and was classified as a UNESCO World Heritage Site in 1982 in recognition of its natural and cultural heritage values.

The organization has collaborated with indigenous groups in Honduras to create a forest guard program that develops ecological guidelines and zoning for the Mesoamerican corridor, including rules for hunting, fishing, forestry and agriculture. As well as community forestry, the group's activities include sustainable agriculture, micro-enterprise development, ecotourism, and advocacy for indigenous land rights.